The aging effects of serial passaging in neural progenitor cells for in vitro neurodegenerative disease modelling

• Main Author: Low, Selwyn Jun Xi
• Other Authors: Surajit Bhattacharyya
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/60266
• Institution: Nanyang Technological University

Neural progenitor cells (NPCs) have been extensively used to model neurodegenerative diseases due to its ability to generate cell types of a neural lineage. As such diseases usually have a late onset, a defined in vitro model that mimics aging would be beneficial to aid the studying of the neurodege...