Using Sequenom to identify KRAS mutations in an Asian cohort of ovarian mucinous cancer

• Main Author: Tiong, Wen Ning
• Other Authors: Chay Wen Yee
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/60297
• Institution: Nanyang Technological University

While there are distinct differences between mucinous epithelial ovarian cancer (mEOC) and the other subtypes of EOC, a standard treatment regimen is followed for all EOC histotypes. KRAS mutations have been observed to occur in relatively high frequencies of 50-60% in mEOC but not in other subtypes...