Understanding how the differential binding of Eg5 onto spindle microtubule causes cohesion fatigue during anti-mitotic cancer treatment
Microtubule and kinesins plays multiple important roles in different phases of mitosis. In this study, we aim to characterize the interaction of kinesin-5 to microtubule using Ligand Tracer technology. To do this, we tried to purify kinesin-5 from whole cell lysate by immuno-precipitation. GFP B-2 a...
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| Format: | Final Year Project |
| Language: | English |
| Published: |
2014
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| Online Access: | http://hdl.handle.net/10356/60306 |
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| Institution: | Nanyang Technological University |
| Language: | English |