Identification and characterization of host cell factors that determine the susceptibility of human and animal cells to coronavirus IBV

• Main Author: Chong, Kelvin Kian Long
• Other Authors: Liu Ding Xiang
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/60608
• Institution: Nanyang Technological University

DExH/D box helicases have been characterized to contribute to a multitude of functions in the host cells, most knowingly involved in the unwinding of RNA in an ATP-dependent manner. Some of these helicases have been shown to affect virus infectivity. Despite advances in understanding Coronavirus rep...