Personalized diagnostics through tumor profiling and circulating cell-free DNA : potential applications in colorectal cancer

• المؤلف الرئيسي: Lau, Yi Ting
• مؤلفون آخرون: School of Biological Sciences
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2014
• الموضوعات: DRNTU::Science::Biological sciences::Genetics
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/60619
• المؤسسة: Nanyang Technological University

This study has been designed to assess the value of circulating cell-free DNA (ccf-DNA) as a personalized diagnostic tool for colorectal cancer (CRC). 26, 10, 14 and 11 somatic mutations were identified through exome capture sequencing pipelines, in the tumors of patient 019, 388, 239 and LHS respec...