Engineering artificial small RNAs for conditional gene silencing in escherichia coli

• Main Author: Tan, Tong Wei
• Other Authors: School of Chemical and Biomedical Engineering
• Format: Final Year Project
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/60856
• Institution: Nanyang Technological University

Conditional gene silencing is a promising technology within the microbiology field. Silencing a gene from a bacteria or cell will greatly change the cell function and morphology. This can be achieved using RNA interference technologies such as small regulatory RNAs (sRNA). However, the specificity o...