Flow test of microfluidic devices

The aim of this report is to study and understand the characteristics of droplets generated using a cross-junction microfluidic device made from Polymethyl-methacrylate (PMMA). Deionised water were dispersed into mineral oil with Span 80 surfactant in square microchannels 200 x 200 μm wide to genera...

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Main Author: Lee, Jocelyn Yu Qi
Other Authors: Tor Shu Beng
Format: Final Year Project
Language:English
Published: 2014
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Online Access:http://hdl.handle.net/10356/60935
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-609352023-03-04T18:42:14Z Flow test of microfluidic devices Lee, Jocelyn Yu Qi Tor Shu Beng School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering The aim of this report is to study and understand the characteristics of droplets generated using a cross-junction microfluidic device made from Polymethyl-methacrylate (PMMA). Deionised water were dispersed into mineral oil with Span 80 surfactant in square microchannels 200 x 200 μm wide to generate monodispersed W/O emulsions. By varying the flow rate ratio and flow rates of dispersed and continuous phases, different flow patterns and droplet lengths were obtained. The effect of surfactant on two-phase flow performance was studied and proved that without surfactant droplets were unable to form. The droplet formation transition from dripping to jetting was expressed in terms of the capillary number of the continuous phase, which shows the effects of viscous force and inertia forces between the two phases on droplet formation. Moreover, the effects of the continuous phase and dispersed phase viscosity on droplet length are investigated. The continuous phase was replaced with sunflower oil to increase the viscosity of the continuous phase. Different concentrations of glycerol were added to DI water to increase the viscosity of dispersed phase. The coefficient of variation in droplet lengths was then calculated to verify the monodispersity of the droplets formed. Attempt has been made to study the stability of droplet generation between the use of flexible (Tygon) and rigid (Teflon) tubing over a range of four flow rates (10µL/min to 40µL/min), with 1 hour interval for every flow rate. It was found out that surfactant concentration also contributes to droplet stability in order to achieve uniform droplet length reduction trends for both types of tubings. The time taken for the droplets to achieve stable length was also observed as part of the stability test and it was found that droplets stabilise faster when rigid tubing was used. The report concludes with the findings and observations in all the experimental works. Several recommendations have been provided for further studies, which helps to improve accuracy and have a better control and understanding of droplet generation using the PMMA device. Bachelor of Engineering (Mechanical Engineering) 2014-06-03T05:49:49Z 2014-06-03T05:49:49Z 2014 2014 Final Year Project (FYP) http://hdl.handle.net/10356/60935 en Nanyang Technological University 105 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Mechanical engineering
spellingShingle DRNTU::Engineering::Mechanical engineering
Lee, Jocelyn Yu Qi
Flow test of microfluidic devices
description The aim of this report is to study and understand the characteristics of droplets generated using a cross-junction microfluidic device made from Polymethyl-methacrylate (PMMA). Deionised water were dispersed into mineral oil with Span 80 surfactant in square microchannels 200 x 200 μm wide to generate monodispersed W/O emulsions. By varying the flow rate ratio and flow rates of dispersed and continuous phases, different flow patterns and droplet lengths were obtained. The effect of surfactant on two-phase flow performance was studied and proved that without surfactant droplets were unable to form. The droplet formation transition from dripping to jetting was expressed in terms of the capillary number of the continuous phase, which shows the effects of viscous force and inertia forces between the two phases on droplet formation. Moreover, the effects of the continuous phase and dispersed phase viscosity on droplet length are investigated. The continuous phase was replaced with sunflower oil to increase the viscosity of the continuous phase. Different concentrations of glycerol were added to DI water to increase the viscosity of dispersed phase. The coefficient of variation in droplet lengths was then calculated to verify the monodispersity of the droplets formed. Attempt has been made to study the stability of droplet generation between the use of flexible (Tygon) and rigid (Teflon) tubing over a range of four flow rates (10µL/min to 40µL/min), with 1 hour interval for every flow rate. It was found out that surfactant concentration also contributes to droplet stability in order to achieve uniform droplet length reduction trends for both types of tubings. The time taken for the droplets to achieve stable length was also observed as part of the stability test and it was found that droplets stabilise faster when rigid tubing was used. The report concludes with the findings and observations in all the experimental works. Several recommendations have been provided for further studies, which helps to improve accuracy and have a better control and understanding of droplet generation using the PMMA device.
author2 Tor Shu Beng
author_facet Tor Shu Beng
Lee, Jocelyn Yu Qi
format Final Year Project
author Lee, Jocelyn Yu Qi
author_sort Lee, Jocelyn Yu Qi
title Flow test of microfluidic devices
title_short Flow test of microfluidic devices
title_full Flow test of microfluidic devices
title_fullStr Flow test of microfluidic devices
title_full_unstemmed Flow test of microfluidic devices
title_sort flow test of microfluidic devices
publishDate 2014
url http://hdl.handle.net/10356/60935
_version_ 1759855472662282240