Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu
The aim of this work is to generate monodispersed alginate microspheres with desired specifications, especially in terms of size and shape. The focus of the experimental procedure will be, not only on the process of generating and collecting the droplets but also to modify, optimize and standardize...
Saved in:
Main Author: | |
---|---|
Other Authors: | |
Format: | Theses and Dissertations |
Language: | English |
Published: |
2014
|
Subjects: | |
Online Access: | http://hdl.handle.net/10356/61098 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Institution: | Nanyang Technological University |
Language: | English |
id |
sg-ntu-dr.10356-61098 |
---|---|
record_format |
dspace |
spelling |
sg-ntu-dr.10356-610982023-03-03T16:06:47Z Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu Kashthuri Thirumurugan School of Chemical and Biomedical Engineering Kang, Yuejun DRNTU::Engineering The aim of this work is to generate monodispersed alginate microspheres with desired specifications, especially in terms of size and shape. The focus of the experimental procedure will be, not only on the process of generating and collecting the droplets but also to modify, optimize and standardize methods and parameters involved for controlled microdroplet production. The purpose of generating these microspheres is to bring in the advantages of controlled processing techniques in microfluidics into the field of oncology. Although based on the overall methodology that has been previously established and verified, the experimental protocol aims to ‘fine-tune’ the minor aspects of droplet generation concept. In this work, tests have been performed in an attempt to isolate the effect of one parameter on the generation and properties of the spheres without influence from other parameters. Such an exercise will be useful in understanding the very fundamentals and physics of microfluidics and to contribute yet another improvised option for producing efficient cancer drug carrier systems. Master of Science (Biomedical Engineering) 2014-06-04T08:44:03Z 2014-06-04T08:44:03Z 2014 2014 Thesis http://hdl.handle.net/10356/61098 en 73 p. application/pdf |
institution |
Nanyang Technological University |
building |
NTU Library |
continent |
Asia |
country |
Singapore Singapore |
content_provider |
NTU Library |
collection |
DR-NTU |
language |
English |
topic |
DRNTU::Engineering |
spellingShingle |
DRNTU::Engineering Kashthuri Thirumurugan Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
description |
The aim of this work is to generate monodispersed alginate microspheres with desired specifications, especially in terms of size and shape. The focus of the experimental procedure will be, not only on the process of generating and collecting the droplets but also to modify, optimize and standardize methods and parameters involved for controlled microdroplet production. The purpose of generating these microspheres is to bring in the advantages of controlled processing techniques in microfluidics into the field of oncology. Although based on the overall methodology that has been previously established and verified, the experimental protocol aims to ‘fine-tune’ the minor aspects of droplet generation concept. In this work, tests have been performed in an attempt to isolate the effect of one parameter on the generation and properties of the spheres without influence from other parameters. Such an exercise will be useful in understanding the very fundamentals and physics of microfluidics and to contribute yet another improvised option for producing efficient cancer drug carrier systems. |
author2 |
School of Chemical and Biomedical Engineering |
author_facet |
School of Chemical and Biomedical Engineering Kashthuri Thirumurugan |
format |
Theses and Dissertations |
author |
Kashthuri Thirumurugan |
author_sort |
Kashthuri Thirumurugan |
title |
Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
title_short |
Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
title_full |
Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
title_fullStr |
Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
title_full_unstemmed |
Generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
title_sort |
generation of alginate encapsules to load nanoparticles for nir induced release for 5-fu |
publishDate |
2014 |
url |
http://hdl.handle.net/10356/61098 |
_version_ |
1759857454134329344 |