Medical image analysis of knee images for sarcopenia detection using mri

• Main Author: Chitradevi
• Other Authors: Poh Chueh Loo
• Format: Theses and Dissertations
• Language: English
• Published: 2014
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/61099
• Institution: Nanyang Technological University

Osteoarthritis is a degenerative syndrome with health impairment leads to decrease in their physical activities, inflammation, stiffness and severe pain in the elderly population. It is necessary for us to know about the mechanism behind Progressive loss of cartilage for the efficient diagnosis and treatment of different stages of osteoarthritis. Now the fast world is expecting an easy and non-invasive technique for diagnosing the disease faster with at most accuracy. So we are going for MRI, which is the most prominent widely used tool to access intra articular surfaces, cartilage in particular. The purpose of calculating the thickness of cartilage is to understand the progressive loss of cartilage and to study the clinical interventions. The aim of the project is to extract and analyze the femoral articular cartilage of the knee joint through medical image analysis. An MRI image was segmented using a number of software, including Matlab and volumetric analysis was performed using the results obtained from these images. We performed manual segmentation, providing anatomical information; in detecting the physical changes in their cartilage structure. Through this we facilitate the clinician to visualize the large amount of data of a particular patient within limited time. Semi–Automatic segmentation include thresholding which would be partially solved by deformable methods, while extracting the cartilage tissue there will be biggest variation in every OA subjects with cartilage in homogeneities and with minimum inter-tissue contrast. Our result helps to analyze the anatomical knee images of five patients and to visualize the thickness of cartilage more rapidly.