Development of oligonucleotides-based inhibitors and studies of the topological phenomenon of mobius DNA
With the aim of exploring new properties and applications of DNA enzymes such as Topoisomerase I and DNA ligase, during this study, the discovery of (1) oligonucletides-based DNA ligase inhibitors and (2) Topological phenomenon of Topoisomerase I and Mobius circular DNA were achieved. In Chap...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2015
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| Online Access: | http://hdl.handle.net/10356/62168 |
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| Institution: | Nanyang Technological University |
| Language: | English |