Carbenoid mediated synthesis of N-heterocycles

Metal carbenoids are highly reactive intermediates that are generated in situ from diazo compounds and transition metals. This work is directed towards the synthesis of N-heterocycles from metal carbenoids, namely the synthesis of pyridines, pyrazine, oxazole and pyrroles in one pot.

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Bibliographic Details
Main Author: Loy, Nicole Shen Yen
Other Authors: Loh Teck Peng
Format: Theses and Dissertations
Language:English
Published: 2015
Subjects:
Online Access:https://hdl.handle.net/10356/62200
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Institution: Nanyang Technological University
Language: English
Description
Summary:Metal carbenoids are highly reactive intermediates that are generated in situ from diazo compounds and transition metals. This work is directed towards the synthesis of N-heterocycles from metal carbenoids, namely the synthesis of pyridines, pyrazine, oxazole and pyrroles in one pot.