Studies on TERRA : telomeric repeat containing RNA

• المؤلف الرئيسي: Reelina Basu
• مؤلفون آخرون: Zhang Li-Feng
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/62529
• المؤسسة: Nanyang Technological University

In this study, we first developed a robust RNA-DNA FISH method for direct observations on the co-localization pattern of Terra and telomeric DNA in the nuclear context To understand the role of Terra in vivo, we monitored X chromosome telomere length change over a long-term cell culture of mouse ES...