Developmental staging of Banf1 : early embryonic lethality in the mouse with doubly-disrupted gene expression

• المؤلف الرئيسي: Ma, Hui Ling
• مؤلفون آخرون: Colin Stewart
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/63468
• المؤسسة: Nanyang Technological University

Barrier-to-Autointegration Factor (BAF) is a 10kDa cytoplasmic/nuclear protein that is encoded by Banf1. BAF exhibits interaction with many key binding partners, with implications in mouse embryonic stem cell development, chromatin reorganization and essential biological gene functions. Homozygous m...