Fabrication of porous collagen scaffold for cardiovascular engineering
Freeze-drying technique was employed to fabricate a porous collagen scaffold to explore its application in the tissue-engineering of cardiovascular system. The effect of thermal conductivity of mold materials and freezing kinetics on the pore structure of the scaffold was investigated. The influence...
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| Format: | Theses and Dissertations |
| Published: |
2008
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| Online Access: | http://hdl.handle.net/10356/6396 |
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| Institution: | Nanyang Technological University |
| Summary: | Freeze-drying technique was employed to fabricate a porous collagen scaffold to explore its application in the tissue-engineering of cardiovascular system. The effect of thermal conductivity of mold materials and freezing kinetics on the pore structure of the scaffold was investigated. The influence of dehydrothermal (DHT) process, 1 -ethyl-3-(3-dimethyl aminopropyl)carbodiimide / N-hydroxysuccinimide (EDC/NHS) and glutaraldehyde (GA) cross-linking on the mechanical property was also studied. |
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