Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network

Owing to numerous merits including improved resolution, increased throughput, reduced analysis time and decreased sample consumption, the microfluidic devices have found a wide spectrum of applications in the biomedical areas such as DNA sequencing, nucleic acid analysis, enzyme assays, immunoassays...

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Main Author: Tang, Gongyue
Other Authors: Yang Chun, Charles
Format: Theses and Dissertations
Published: 2008
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Online Access:https://hdl.handle.net/10356/6445
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-64452023-03-11T17:51:00Z Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network Tang, Gongyue Yang Chun, Charles School of Mechanical and Aerospace Engineering DRNTU::Engineering::Mechanical engineering::Fluid mechanics Owing to numerous merits including improved resolution, increased throughput, reduced analysis time and decreased sample consumption, the microfluidic devices have found a wide spectrum of applications in the biomedical areas such as DNA sequencing, nucleic acid analysis, enzyme assays, immunoassays, etc. In microfluidic devices, electrokinetic transport, which in principle exploits two driving mechanisms - electrophoresis and electroosmosis, is used extensively to control liquid buffer flow and manipulate samples of nano/pico-liter volumes. It is known that the presence of Joule heating imposes limitations to the performance of electrokinetic transport. However, systematic investigations of the Joule heating and its effects on electroosmotic flow and electrokinetic mass transport based on the rigorous mathematical models still remain limited. In light of this, this dissertation provides a fundamental, systematic and in-depth exploration on the Joule heating and its effect on the electrokinetic transport in microfluidic systems. DOCTOR OF PHILOSOPHY (MPE) 2008-09-17T11:15:07Z 2008-09-17T11:15:07Z 2006 2006 Thesis Tang, G. (2006). Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/6445 10.32657/10356/6445 Nanyang Technological University application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Engineering::Mechanical engineering::Fluid mechanics
spellingShingle DRNTU::Engineering::Mechanical engineering::Fluid mechanics
Tang, Gongyue
Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
description Owing to numerous merits including improved resolution, increased throughput, reduced analysis time and decreased sample consumption, the microfluidic devices have found a wide spectrum of applications in the biomedical areas such as DNA sequencing, nucleic acid analysis, enzyme assays, immunoassays, etc. In microfluidic devices, electrokinetic transport, which in principle exploits two driving mechanisms - electrophoresis and electroosmosis, is used extensively to control liquid buffer flow and manipulate samples of nano/pico-liter volumes. It is known that the presence of Joule heating imposes limitations to the performance of electrokinetic transport. However, systematic investigations of the Joule heating and its effects on electroosmotic flow and electrokinetic mass transport based on the rigorous mathematical models still remain limited. In light of this, this dissertation provides a fundamental, systematic and in-depth exploration on the Joule heating and its effect on the electrokinetic transport in microfluidic systems.
author2 Yang Chun, Charles
author_facet Yang Chun, Charles
Tang, Gongyue
format Theses and Dissertations
author Tang, Gongyue
author_sort Tang, Gongyue
title Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
title_short Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
title_full Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
title_fullStr Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
title_full_unstemmed Thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
title_sort thermal aspects of electrokinetic flow and capillary electrophoresis in microchannel network
publishDate 2008
url https://hdl.handle.net/10356/6445
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