The role of topography in the micro-fabrication of an intervertebral disc

• Main Author: Lim, Chee Seong
• Other Authors: Kang Yuejun
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/64734
• Institution: Nanyang Technological University

Cell behavior can be manipulated by the topography of the culture substrate. In this study, we examined the cell alignment of multipotent mesenchymal stem cell (MSC) on a grill topographical pattern of porous poly(L-lactide/Caprolactone) (PLC) substrate. Electron microscopy showed that MSC integrate...