Investigation of cocktails of growth factors for proliferative zonal growth plate using multi-array microfluidic platform

• Main Author: Yeo, Qiu Ju
• Other Authors: Kang Yuejun
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/65133
• Institution: Nanyang Technological University

A major problem in the development of engineering an in-vitro growth plate is the premature entrance of the chondrocytes to the hypertrophic stage without the production of Collagen type II (Col2). The study explored the use of a cocktail of growth factors, in particularly, TGF-β3, FGF-2 and insulin...