Development of an annulus fibrosus tissue model with ascorbic acid induced mesenchymal stem cells

• Main Author: Cheong, Shirlynn Mei Ling
• Other Authors: Kang Yuejun
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/65231
• Institution: Nanyang Technological University

The Annulus Fibrosus (AF) in the Intervetebral Disc (IVD) contains Type I and II Collagen, Aggrecans and Proteoglycans. When experiencing disc degeneration, the IVD composition tends to alter, leading to a thinner disc as well as losing its natural function of protecting our spine and absorbing shoc...