SIRNA-loaded PLGA microspheres for regulation of macrophage gene expression

• Main Author: Lin, Junquan
• Other Authors: Chong Seow Khoon, Mark
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/65233
• Institution: Nanyang Technological University

Macrophage polarization has been shown to be a key event in inflammatory processes. It follows that manipulation of macrophage states may offer a powerful tool to control innate immune responses. In this project, we studied the use of Poly (lactic-co-glycolic acid) PLGA microspheres to deliver small...