Identification of AHR and hypoxia co-regulated immune target genes as potential factors of inflammation-driven oncogenesis

• المؤلف الرئيسي: Zaiden, Norazean
• مؤلفون آخرون: Lee Kian Leong
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2015
• الموضوعات: DRNTU::Science::Biological sciences::Molecular biology
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/65300

The transcription factors AHR and HIFs dimerize with the common co-activator ARNT during adaptive responses to xenobiotic exposure and oxygen tension. This cross-talk may subsequently modulate inflammation and/or physiological adaptation via immune cellular survival and maturation. Dysregulation of...