Two algorithmic problems in analyzing genetic and epigenetic variations

• 主要作者: Sun, Ruimin
• 其他作者: Chen Xin
• 格式: Theses and Dissertations
• 語言: English
• 出版: 2015
• 主題: DRNTU::Science::Mathematics::Discrete mathematics::Algorithms; DRNTU::Science::Biological sciences::Genetics
• 在線閱讀: https://hdl.handle.net/10356/65312
• 機構: Nanyang Technological University

Single nucleotide polymorphism (SNP) is the most common type of genetic variations.Accurate detection of SNPs is crucial to many downstream studies. To detect SNPs, MALDI-TOF mass spectrometry combined with base-specific cleavage reactions has been employed in many experiments. A new SNP detecting al...