Use of chemical elicitors to stimulate the production of antimicrobial natural products from mangrove microorganisms

• Main Author: Ongko, Juwinda
• Other Authors: Liang Zhao-Xun
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Biochemistry
• Online Access: http://hdl.handle.net/10356/65379
• Institution: Nanyang Technological University

Actinomycetes are widely recognized as a highly productive source of antimicrobial natural products. However, discovery of novel compounds was unfavourable due to presence of silent antibiotic-producing gene clusters. This study used chemical elicitors to stimulate cryptic clusters to produce novel...