Effect of stress on neuroinflammation in the substantia nigra and striatum of LRRK2 (R1441G) mouse model for Parkinson’s disease

• Main Author: Chen, Jiayi
• Other Authors: Zoë Bichler
• Format: Final Year Project
• Language: English
• Published: 2015
• Subjects: DRNTU::Science::Biological sciences::Human anatomy and physiology::Neurobiology
• Online Access: http://hdl.handle.net/10356/65388
• Institution: Nanyang Technological University

Stress is known to have a pro-inflammatory effect on the CNS. Neuroinflammation mediated by microglia activation and proliferation in the substantia nigra and striatum may play a significant role in PD progression. Our objective in this project was to investigate the effect of stress on neuroinflamm...