Biochemical and structural analysis on the molecular interaction between FK-506 binding protein (FKBP) 38 and anti-apoptotic protein BCL-2

FK506 binding protein (FKBP) 38, which is a tripartite TPR domain-containing member in the FKBP family, can help Bcl-2 localize at the mitochondrial membrane and modulate apoptosis. The regulation of Bcl-2 function by forming heterodimeric complexes with its pro-apoptotic partners is well studied. B...

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Bibliographic Details
Main Author: Kang, Congbao
Other Authors: Yoon, Ho Sup
Format: Theses and Dissertations
Published: 2008
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Institution: Nanyang Technological University