Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds
The prevalence of five-membered carbocyclic framework in natural products and biologically relevant compounds has propelled the development of Nazarov cyclization into a reliable synthetic method for construction of cyclopentanoid compounds. Some of the critical advances with regard to control of re...
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sg-ntu-dr.10356-659732023-02-28T23:55:28Z Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds Ronny, William Liu Xuewei School of Physical and Mathematical Sciences DRNTU::Science::Physics The prevalence of five-membered carbocyclic framework in natural products and biologically relevant compounds has propelled the development of Nazarov cyclization into a reliable synthetic method for construction of cyclopentanoid compounds. Some of the critical advances with regard to control of regioselectivity in the elimination step, understanding substituent effects on reactivity, the use of alternative substrate as precursor to pentadienyl cation and the development of asymmetric reaction, which have greatly increased the synthetic utility of Nazarov cyclization will be discussed in Chapter 1. Doctor of Philosophy (SPMS) 2016-02-10T06:19:55Z 2016-02-10T06:19:55Z 2016 Thesis http://hdl.handle.net/10356/65973 en 234 p. application/pdf |
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DRNTU::Science::Physics |
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DRNTU::Science::Physics Ronny, William Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| description |
The prevalence of five-membered carbocyclic framework in natural products and biologically relevant compounds has propelled the development of Nazarov cyclization into a reliable synthetic method for construction of cyclopentanoid compounds. Some of the critical advances with regard to control of regioselectivity in the elimination step, understanding substituent effects on reactivity, the use of alternative substrate as precursor to pentadienyl cation and the development of asymmetric reaction, which have greatly increased the synthetic utility of Nazarov cyclization will be discussed in Chapter 1. |
| author2 |
Liu Xuewei |
| author_facet |
Liu Xuewei Ronny, William |
| format |
Theses and Dissertations |
| author |
Ronny, William |
| author_sort |
Ronny, William |
| title |
Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| title_short |
Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| title_full |
Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| title_fullStr |
Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| title_full_unstemmed |
Development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| title_sort |
development of novel interrupted nazarov cyclizations for construction of diverse cyclopentanoid compunds |
| publishDate |
2016 |
| url |
http://hdl.handle.net/10356/65973 |
| _version_ |
1759857492105363456 |