Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells
Macrophages, as crucial mediators of an innate immune response, exhibit functional plasticity by playing an essential role in both the initiation and resolution of inflammation. Production of the pro-inflammatory cytokine IL-1β, via caspase-11 activation during Gram-negative bacterial infections, an...
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| Format: | Theses and Dissertations |
| Language: | English |
| Published: |
2016
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| Online Access: | https://hdl.handle.net/10356/66024 |
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| Institution: | Nanyang Technological University |
| Language: | English |