Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells

• المؤلف الرئيسي: Sin, Wei Xiang
• مؤلفون آخرون: Chin Keh-Chuang
• التنسيق: Theses and Dissertations
• اللغة: English
• منشور في: 2016
• الموضوعات: DRNTU::Science::Biological sciences
• الوصول للمادة أونلاين: https://hdl.handle.net/10356/66024
• المؤسسة: Nanyang Technological University

Macrophages, as crucial mediators of an innate immune response, exhibit functional plasticity by playing an essential role in both the initiation and resolution of inflammation. Production of the pro-inflammatory cytokine IL-1β, via caspase-11 activation during Gram-negative bacterial infections, an...