Interleukin-2 receptor activation by an anti-IL-2Rβ/γc bispecific antibody
Interleukin-2 (IL-2) is an immunostimulatory cytokine that acts as a mitogen for T cells and natural killer (NK) cells. There is an increasing interest in using IL-2 as a therapeutic agent to combat cancers and infectious pathogens. However, it has not been successfully utilized in a clinical sett...
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Format: | Thesis-Doctor of Philosophy |
Language: | English |
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Nanyang Technological University
2016
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Online Access: | http://hdl.handle.net/10356/66329 |
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Institution: | Nanyang Technological University |
Language: | English |