Identification and characterisation of novel human dendritic cell progenitors

• Main Author: See, Peter Chi Ee
• Other Authors: Florent Ginhoux
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: https://hdl.handle.net/10356/67316
• Institution: Nanyang Technological University

Dendritic cells (DCs) are professional antigen presenting cells that initiate the immune response. They are heterogeneous and are broadly classified into three groups – two major subsets of conventional DCs (cDC) named cDC1 and cDC2, and plasmacytoid DC (pDC). Each subset has unique transcription fa...