Oxidative phosphorylation as a drug target space in mycobacteria

• Main Author: Low, Samuel Xin Zher
• Other Authors: Kevin Pethe
• Format: Final Year Project
• Language: English
• Published: 2016
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/68281
• Institution: Nanyang Technological University

The emergence of drug-resistant Mycobacterium tuberculosis (Mtb) and latent TB infection has emphasised the need to identify novel drug targets which are capable of eliminating both drug resistant, and dormant Mtb. The recognition of energy metabolism as an essential pathway for survival in all form...