Experimental investigation of a bi-leaflet heart valve

Babies with congenital heart defects require high risk surgeries at birth or adolescence. As the patient matures, replacement of larger artificial valves to accommodate their growth would require additional surgeries. The objective of this experiment is to reduce the amount of re-surgeries required...

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書目詳細資料
主要作者: Chan, Kah Ming
其他作者: Yeo Joon Hock
格式: Final Year Project
語言:English
出版: 2016
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在線閱讀:http://hdl.handle.net/10356/68518
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機構: Nanyang Technological University
語言: English
實物特徵
總結:Babies with congenital heart defects require high risk surgeries at birth or adolescence. As the patient matures, replacement of larger artificial valves to accommodate their growth would require additional surgeries. The objective of this experiment is to reduce the amount of re-surgeries required by determining the compatibly of the artificial valves upon the change in diameters of the artery with growth and the method of which the valve was sutured. The valves used are made of expanded polytetrafluoroethylene (ePTFE) with a 13mm diameter kept constant for the various diameters of the silicon conduits ranging from 13mm, 17mm and 21mm. From the experimental results of the 3 different diameters of silicon conduits, the percentage of regurgitation ranged from 7% to 76%.The results showed that the increase in percentage of regurgitation increases linearly with the increase in the diameter of the lumen. Methods used in suturing of the valve affected the regurgitation rate was proven with the experimental results. In comparison to previous experimental results by Jowell Cheng, a correlation found between the 13-21mm silicon conduits yield a 10% variation which can be attributed to different experimental conditions.