Tissue engineered interface with microfluidics
Microfluidics technology started around the beginning of 1980s and has been used in various applications such as DNA chip, Lab-on-a-Chip and cell counting technology etc. due to its advantages over conventional devices. Interface tissue engineering (ITE) has been widely applied to repair injured...
Saved in:
| Main Author: | |
|---|---|
| Other Authors: | |
| Format: | Final Year Project |
| Language: | English |
| Published: |
2016
|
| Subjects: | |
| Online Access: | http://hdl.handle.net/10356/68548 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| Institution: | Nanyang Technological University |
| Language: | English |
| Summary: | Microfluidics technology started around the beginning of 1980s and has been used in various
applications such as DNA chip, Lab-on-a-Chip and cell counting technology etc. due to its
advantages over conventional devices. Interface tissue engineering (ITE) has been widely
applied to repair injured tissues at tissue interface. Therefore, the purpose of this project is to
combine these two technology. Due to the novelty of these project, optimization protocols will
be established. Flow rate will be 0.0044ml/min, concentration of agarose will be 3%, in-situ
staining and washing will take 20 minutes. Results showed that in static culturing system,
there is no gradient of calcium phosphate which support our hypothesis. In addition, results
from dynamic culturing system did not show any significant gradient. Therefore, more studies
have to be done to achieve this gradient. Once this platform is established, this can be
translated to investigate osteochondral construct. |
|---|