Basic studies of polymeric gels with specific applications to drug delivery applications

The objectives of this study are (i) to acquire detailed fundamental information on macromolecular movement and association behavior during the formation of clusters in the sol state in order to elucidate the gelation mechanisms; (ii) to determine fractal structures, scaling laws and microstructure...

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Main Author: Li, Lin
Other Authors: School of Mechanical and Production Engineering
Format: Research Report
Published: 2008
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Online Access:http://hdl.handle.net/10356/6879
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Institution: Nanyang Technological University
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spelling sg-ntu-dr.10356-68792023-03-04T18:09:55Z Basic studies of polymeric gels with specific applications to drug delivery applications Li, Lin School of Mechanical and Production Engineering DRNTU::Engineering::Mechanical engineering The objectives of this study are (i) to acquire detailed fundamental information on macromolecular movement and association behavior during the formation of clusters in the sol state in order to elucidate the gelation mechanisms; (ii) to determine fractal structures, scaling laws and microstructures; and (iii) to study molecular diffusion of a guest substance immobilized in a hydrogel. Several thermoreversible gelling systems are selected for this project, which include methylcellulose, hydroxypropyl methylcellulose, agar, ?-carrageenan, gelatin, Pluronic triblock copolymers (PEO-PPO-PEO and PPO-PEO-PPO copolymers), etc. The effects of polymer concentration, blending composition, temperature, salts, surfactants, magnetic field, etc are examined. 2008-09-17T14:36:08Z 2008-09-17T14:36:08Z 2004 2004 Research Report http://hdl.handle.net/10356/6879 Nanyang Technological University application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
topic DRNTU::Engineering::Mechanical engineering
spellingShingle DRNTU::Engineering::Mechanical engineering
Li, Lin
Basic studies of polymeric gels with specific applications to drug delivery applications
description The objectives of this study are (i) to acquire detailed fundamental information on macromolecular movement and association behavior during the formation of clusters in the sol state in order to elucidate the gelation mechanisms; (ii) to determine fractal structures, scaling laws and microstructures; and (iii) to study molecular diffusion of a guest substance immobilized in a hydrogel. Several thermoreversible gelling systems are selected for this project, which include methylcellulose, hydroxypropyl methylcellulose, agar, ?-carrageenan, gelatin, Pluronic triblock copolymers (PEO-PPO-PEO and PPO-PEO-PPO copolymers), etc. The effects of polymer concentration, blending composition, temperature, salts, surfactants, magnetic field, etc are examined.
author2 School of Mechanical and Production Engineering
author_facet School of Mechanical and Production Engineering
Li, Lin
format Research Report
author Li, Lin
author_sort Li, Lin
title Basic studies of polymeric gels with specific applications to drug delivery applications
title_short Basic studies of polymeric gels with specific applications to drug delivery applications
title_full Basic studies of polymeric gels with specific applications to drug delivery applications
title_fullStr Basic studies of polymeric gels with specific applications to drug delivery applications
title_full_unstemmed Basic studies of polymeric gels with specific applications to drug delivery applications
title_sort basic studies of polymeric gels with specific applications to drug delivery applications
publishDate 2008
url http://hdl.handle.net/10356/6879
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