Computational integrative genomics approach to refine breast cancer genetic grading and prognosis

• Main Author: Luay Aswad
• Other Authors: Kwoh Chee Keong
• Format: Theses and Dissertations
• Language: English
• Published: 2016
• Subjects: DRNTU::Engineering::Computer science and engineering::Computing methodologies::Pattern recognition
• Online Access: http://hdl.handle.net/10356/69043
• Institution: Nanyang Technological University

Tumor heterogeneity is one of the major challenges of breast cancer (BC) classification and patients’ treatment. Histologic grading classifies BC into three categories: 1, 2 and 3 (HG1, HG2, and HG3, respectively). HG has so far been one of the most powerful BC prognostic markers for patients’ survi...