Mechanistic insights into Escherichia coli Alkyl hydroperoxide subunit C (AhpC) and the molecular switch for peroxide robustness

Typical 2-Cys peroxiredoxins (Prxs) are mainly involved in antioxidant defense and the signal transduction pathway of H2O2 by undergoing inactivation once intracellular H2O2 concentrations exceed the threshold. This inactivation mechanism is only present in eukaryotes. In order to glean molecular in...

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Bibliographic Details
Main Author: Sek, Mun Foong
Other Authors: School of Biological Sciences
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:http://hdl.handle.net/10356/69130
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Institution: Nanyang Technological University
Language: English