Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy

The prevalence of obesity globally today has become significantly prominent and this has posed serious challenges and problems for professionals in the health sector to combat. The rising side effects of existing synthetic drugs used to medically treat obesity have also been concerning and the need...

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Main Author: Asyifah Mohamed Rashid
Other Authors: Zhang Dawei
Format: Theses and Dissertations
Language:English
Published: 2016
Subjects:
Online Access:https://hdl.handle.net/10356/69425
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-694252023-03-01T00:01:11Z Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy Asyifah Mohamed Rashid Zhang Dawei Lee Soo Ying School of Physical and Mathematical Sciences DRNTU::Science::Chemistry The prevalence of obesity globally today has become significantly prominent and this has posed serious challenges and problems for professionals in the health sector to combat. The rising side effects of existing synthetic drugs used to medically treat obesity have also been concerning and the need for alternative measures of treatment is greatly in demand. In this thesis, a range of studies being done to investigate the potential of natural components, particularly, fruit waste components, as an alternative source for obesity treatment will be discussed. The elucidation of bioactive compounds present in the respective active fruit waste components will be identified and its biomechanism were investigated. In addition, comparative study to investigate the difference in effectiveness between the waste component and flesh of a fruit as well ripening stages of a fruit were also investigated in two separate chapters of this thesis. Finally, for a holistic investigation of experimental extraction condition, an optimization study to explore the most optimal condition to yield the highest amount of bioactive compound(s) from a fruit component was also determined. DOCTOR OF PHILOSOPHY (SPMS) 2016-12-29T08:08:09Z 2016-12-29T08:08:09Z 2016 Thesis Asyifah Mohamed Rashid. (2016). Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy. Doctoral thesis, Nanyang Technological University, Singapore. https://hdl.handle.net/10356/69425 10.32657/10356/69425 en 204 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Science::Chemistry
spellingShingle DRNTU::Science::Chemistry
Asyifah Mohamed Rashid
Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
description The prevalence of obesity globally today has become significantly prominent and this has posed serious challenges and problems for professionals in the health sector to combat. The rising side effects of existing synthetic drugs used to medically treat obesity have also been concerning and the need for alternative measures of treatment is greatly in demand. In this thesis, a range of studies being done to investigate the potential of natural components, particularly, fruit waste components, as an alternative source for obesity treatment will be discussed. The elucidation of bioactive compounds present in the respective active fruit waste components will be identified and its biomechanism were investigated. In addition, comparative study to investigate the difference in effectiveness between the waste component and flesh of a fruit as well ripening stages of a fruit were also investigated in two separate chapters of this thesis. Finally, for a holistic investigation of experimental extraction condition, an optimization study to explore the most optimal condition to yield the highest amount of bioactive compound(s) from a fruit component was also determined.
author2 Zhang Dawei
author_facet Zhang Dawei
Asyifah Mohamed Rashid
format Theses and Dissertations
author Asyifah Mohamed Rashid
author_sort Asyifah Mohamed Rashid
title Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
title_short Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
title_full Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
title_fullStr Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
title_full_unstemmed Selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
title_sort selective tropical fruit waste component exhibiting adipocyte differentiation inhibition, a future anti-obesity therapeutic strategy
publishDate 2016
url https://hdl.handle.net/10356/69425
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