Injectable hydrogels as matrix to retain microparticles for controlled delivery of anti-VEGF proteins for ocular applications

• Main Author: Chong, Wei Woon
• Other Authors: Subramanian Venkatraman
• Format: Final Year Project
• Language: English
• Published: 2017
• Subjects: DRNTU::Engineering::Materials
• Online Access: http://hdl.handle.net/10356/70120
• Institution: Nanyang Technological University

Wet age-related macular degeneration (AMD) or diabetic macular edema (DME) are potentially retinal diseases and they are treated by monthly or bimonthly intravitreal injections of anti-vascular endothelial growth factor (VEGF) agents such as aflibercept (Eylea®) and ranibizumab (Lucentis®). Because...