Targeting the Bromodomain-containing protein 4 in ovarian clear cell carcinoma

• Main Author: Wong, Erica Shiyi
• Other Authors: Vinay Tergaonkar
• Format: Final Year Project
• Language: English
• Published: 2017
• Subjects: DRNTU::Science
• Online Access: http://hdl.handle.net/10356/70625
• Institution: Nanyang Technological University

Ovarian clear cell carcinoma (OCCC) is the second most common histopathological subtype of ovarian carcinoma (OC), making up 5-25% of all OC. Current treatment utilizing combination chemotherapy with cisplatin and paclitaxel have low efficacy with a 5-year survival rate of only 12%. Bromodomain-cont...