Deep learning system for brain tumor grading classification

The project aims to classify about 300 high- and low-grade glioma cases from MICCAI - BRATS 2015 Challenge Dataset. Each record has T1 MRI, T1 contrast-enhanced MRI, T2 MRI, and T2 Flair MRI. We use a convolutional neural network architecture for grade classification of each case. The main hallma...

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Main Author: Nhan, Tran Ho Chi
Other Authors: Lin Zhiping
Format: Final Year Project
Language:English
Published: 2017
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Online Access:http://hdl.handle.net/10356/72015
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-720152023-07-07T16:49:11Z Deep learning system for brain tumor grading classification Nhan, Tran Ho Chi Lin Zhiping School of Electrical and Electronic Engineering A*STAR Institute for Infocomm Research DRNTU::Engineering::Electrical and electronic engineering The project aims to classify about 300 high- and low-grade glioma cases from MICCAI - BRATS 2015 Challenge Dataset. Each record has T1 MRI, T1 contrast-enhanced MRI, T2 MRI, and T2 Flair MRI. We use a convolutional neural network architecture for grade classification of each case. The main hallmark of the architecture is the utilization of spatial information of a tumor by using 3D convolutional layers with 3D kernels and 3D max pool layers. Since GPU memory is an essential factor of quickly training a neural network, the number of filters in each layer is carefully reduced and tested so that it won’t cause the network to lose its ability to characterize important features of the volume dataset. Furthermore, the size of each input volume is also reduced in a way that still maintains the crucial tumor features. This was achieved by cropping only the part of brain which contains the tumor, and forwarding it through 5 paths of 3D convolutional layers and 3D max pool layers. To objectively maintain the trustworthiness of the network, the small amount of data set - 223 high-grade cases and 57 low-grade cases was overcome by cross-validation, i.e. we split the data set to multiple train-test sets so that the network’s performance can be seen on all test cases. Finally, stochastic gradient descent was implemented at the input phase of the network by loading small batches of random data from the training set instead of expensively shuffling the whole training set for many iterations. The quality of the network is periodically assessed using the test set for each train-test run. The result shows an improvement with the 3D CNN and deeper architecture compared with the previous 2D CNN network. Bachelor of Engineering 2017-05-23T07:40:13Z 2017-05-23T07:40:13Z 2017 Final Year Project (FYP) http://hdl.handle.net/10356/72015 en Nanyang Technological University 46 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Electrical and electronic engineering
spellingShingle DRNTU::Engineering::Electrical and electronic engineering
Nhan, Tran Ho Chi
Deep learning system for brain tumor grading classification
description The project aims to classify about 300 high- and low-grade glioma cases from MICCAI - BRATS 2015 Challenge Dataset. Each record has T1 MRI, T1 contrast-enhanced MRI, T2 MRI, and T2 Flair MRI. We use a convolutional neural network architecture for grade classification of each case. The main hallmark of the architecture is the utilization of spatial information of a tumor by using 3D convolutional layers with 3D kernels and 3D max pool layers. Since GPU memory is an essential factor of quickly training a neural network, the number of filters in each layer is carefully reduced and tested so that it won’t cause the network to lose its ability to characterize important features of the volume dataset. Furthermore, the size of each input volume is also reduced in a way that still maintains the crucial tumor features. This was achieved by cropping only the part of brain which contains the tumor, and forwarding it through 5 paths of 3D convolutional layers and 3D max pool layers. To objectively maintain the trustworthiness of the network, the small amount of data set - 223 high-grade cases and 57 low-grade cases was overcome by cross-validation, i.e. we split the data set to multiple train-test sets so that the network’s performance can be seen on all test cases. Finally, stochastic gradient descent was implemented at the input phase of the network by loading small batches of random data from the training set instead of expensively shuffling the whole training set for many iterations. The quality of the network is periodically assessed using the test set for each train-test run. The result shows an improvement with the 3D CNN and deeper architecture compared with the previous 2D CNN network.
author2 Lin Zhiping
author_facet Lin Zhiping
Nhan, Tran Ho Chi
format Final Year Project
author Nhan, Tran Ho Chi
author_sort Nhan, Tran Ho Chi
title Deep learning system for brain tumor grading classification
title_short Deep learning system for brain tumor grading classification
title_full Deep learning system for brain tumor grading classification
title_fullStr Deep learning system for brain tumor grading classification
title_full_unstemmed Deep learning system for brain tumor grading classification
title_sort deep learning system for brain tumor grading classification
publishDate 2017
url http://hdl.handle.net/10356/72015
_version_ 1772826565058494464