Molecular characterisation of the effects of classical chemotherapy on Candida albicans and systemic candidiasis

• Main Author: Teoh, Flora Poh Leng
• Other Authors: Norman Xaver Pavelka
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Microorganisms; DRNTU::Science::Biological sciences::Evolution; DRNTU::Science::Biological sciences::Molecular biology
• Online Access: http://hdl.handle.net/10356/72226
• Institution: Nanyang Technological University

Due to chemotherapy-induced immunosuppression and epithelial barrier disruption, cancer patients are well-known to be at increased risk of opportunistic infection, such as those caused by the dimorphic fungus Candida albicans. While effects of chemotherapy on the host are well documented, little is...