Investigating the effect of stress on a mouse model for Parkinson’s disease

• المؤلف الرئيسي: Yeo, Natalie
• مؤلفون آخرون: Zoë Bichler
• التنسيق: Final Year Project
• اللغة: English
• منشور في: 2017
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/72380

Parkinson’s disease (PD) is the second most prevalent neurodegenerative disorder. Among the genes found to be mutated in PD, the LRRK2 (R1441G) mutation, frequent in the Basque country, shows high penetrance and has been used to generate a genetic mouse model for PD. With chronic stress known to agg...