Characterization of the role of Irisin in skeletal muscle growth and repair

• Main Author: Musarrat Maisha Reza
• Other Authors: Craig Desmond McFarlane
• Format: Theses and Dissertations
• Language: English
• Published: 2017
• Subjects: DRNTU::Science::Biological sciences
• Online Access: http://hdl.handle.net/10356/72482
• Institution: Nanyang Technological University

Exercise stimulates the expression of PPAR-γ co-activator I-α (PGC I-α), which in turn increases the levels of the myokine, Irisin. Irisin is synthesized as part of a 209 amino acid (aa) long precursor protein, Fibronectin Type III Domain Containing Protein 5 (FNDC5), which is proteolytically cleave...