Multifunctional polymeric nanomaterials for cancer imaging and therapy

This thesis summarized my postgraduate research work on the design and synthesis of multifunctional polymers self-assembled for cancer imaging and therapy. It would focus on the fluorescent polymers from visible to near infrared (NIR) region with good biodegradability and bio-compatibility that perf...

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Main Author: Huang, Shuo
Other Authors: Wang Mingfeng
Format: Theses and Dissertations
Language:English
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/10356/72673
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Institution: Nanyang Technological University
Language: English
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spelling sg-ntu-dr.10356-726732023-03-03T16:03:41Z Multifunctional polymeric nanomaterials for cancer imaging and therapy Huang, Shuo Wang Mingfeng School of Chemical and Biomedical Engineering DRNTU::Engineering::Bioengineering This thesis summarized my postgraduate research work on the design and synthesis of multifunctional polymers self-assembled for cancer imaging and therapy. It would focus on the fluorescent polymers from visible to near infrared (NIR) region with good biodegradability and bio-compatibility that performed highly fluorescence and robust photostability for long-term bioimaging. Besides, the biocompatible polymers with NIR absorption were investigated to show excellent photothermal conversion for cancer therapy. Finally, these multifunctional polymers were explored as theranostic nanomaterials that incorporated fluorescence imaging or photoacoustic imaging with cancer therapy strategies. It could not only diagnose disease sites by strong contrast signal, but also could treat diseased tissues by releasing encapsulated drug or heat generated by photothermal effect. Doctor of Philosophy (SCBE) 2017-09-15T01:07:40Z 2017-09-15T01:07:40Z 2017 Thesis Huang, S. (2017). Multifunctional polymeric nanomaterials for cancer imaging and therapy. Doctoral thesis, Nanyang Technological University, Singapore. http://hdl.handle.net/10356/72673 10.32657/10356/72673 en 224 p. application/pdf
institution Nanyang Technological University
building NTU Library
continent Asia
country Singapore
Singapore
content_provider NTU Library
collection DR-NTU
language English
topic DRNTU::Engineering::Bioengineering
spellingShingle DRNTU::Engineering::Bioengineering
Huang, Shuo
Multifunctional polymeric nanomaterials for cancer imaging and therapy
description This thesis summarized my postgraduate research work on the design and synthesis of multifunctional polymers self-assembled for cancer imaging and therapy. It would focus on the fluorescent polymers from visible to near infrared (NIR) region with good biodegradability and bio-compatibility that performed highly fluorescence and robust photostability for long-term bioimaging. Besides, the biocompatible polymers with NIR absorption were investigated to show excellent photothermal conversion for cancer therapy. Finally, these multifunctional polymers were explored as theranostic nanomaterials that incorporated fluorescence imaging or photoacoustic imaging with cancer therapy strategies. It could not only diagnose disease sites by strong contrast signal, but also could treat diseased tissues by releasing encapsulated drug or heat generated by photothermal effect.
author2 Wang Mingfeng
author_facet Wang Mingfeng
Huang, Shuo
format Theses and Dissertations
author Huang, Shuo
author_sort Huang, Shuo
title Multifunctional polymeric nanomaterials for cancer imaging and therapy
title_short Multifunctional polymeric nanomaterials for cancer imaging and therapy
title_full Multifunctional polymeric nanomaterials for cancer imaging and therapy
title_fullStr Multifunctional polymeric nanomaterials for cancer imaging and therapy
title_full_unstemmed Multifunctional polymeric nanomaterials for cancer imaging and therapy
title_sort multifunctional polymeric nanomaterials for cancer imaging and therapy
publishDate 2017
url http://hdl.handle.net/10356/72673
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