Iridocorneal angle and fundus imaging with integrated flexible handheld probe

• Main Author: Lim, Yong Siong
• Other Authors: Murukeshan Vadakke Matham
• Format: Final Year Project
• Language: English
• Published: 2017
• Subjects: DRNTU::Engineering
• Online Access: http://hdl.handle.net/10356/73032
• Institution: Nanyang Technological University

The aim of the research is to develop a flexible handheld probe that has a dual function of image the ICA (iridocorneal angle) and fundus in the eye for ophthalmology photography specifically for glaucoma diagnosis and prognosis. The design of the ocular imaging probe consists of a CCD camera and a 2x2 LED circular array. Important design parameters for considerations includes array radius r, working distance l, illumination angle α and viewing angle θLED. Due to the natural phenomenon of total internal reflection, image capturing would be extremely challenging. A possible solution would be to make use of LED array for near field irradiance coupled with the use of an ophthalmic gel with suitable refractive index which would potentially solve the problem. Imaging tests were conducted on porcine eyes model ex vivo due to its physiological similarity to the human eyes. The results reflected promising results as the images of ICA and fundus captured via the probe were of high quality where critical structures such as the sclera spur, iris root, ciliary body band and iris root are easily identifiable. These results validate the probe’s capability for adoption as a feasible form of ophthalmic instrument due to its cost efficiency, ease of operation relative to current imaging. The research also reflects the potential of use in a real clinical setting on human eye in vivo.