Investigating the solution structure of G-rich DNA and RNA using AFM

• Main Author: Bose, Krishnashish
• Other Authors: Phan Anh Tuan
• Format: Theses and Dissertations
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences::Biophysics; DRNTU::Science::Physics::Atomic physics::Solid state physics
• Online Access: http://hdl.handle.net/10356/73074
• Institution: Nanyang Technological University

G-rich DNA/RNA sequences are highly dynamic and diverse in nature as they can adopt a myriad of secondary structures in physiologically relevant conditions. Several biologically relevant G-rich repeat motif DNA sequences are known to form higher-order G-quadruplexes, but little is known about their...