Part I. Synthesis of chiral 3-substituted indanones via transition-metal-catalyzed reductive heck reaction. Part II. Tert-butyl peroxybenzoate promoted oxidative coupling between heteroarenes and alkanes

• المؤلف الرئيسي: Lei, Kaining
• مؤلفون آخرون: Tan Choon Hong
• التنسيق: Thesis-Doctor of Philosophy
• اللغة: English
• منشور في: Nanyang Technological University 2018
• الموضوعات: DRNTU::Science
• الوصول للمادة أونلاين: http://hdl.handle.net/10356/73253
• المؤسسة: Nanyang Technological University

A new approach to chiral 3-substituted indanones via palladium-catalyzed reductive Heck reaction with excellent yields (>80%) and enantioselectivities (>90% ee) had been developed. Substrates with ortho-, para- substitution, or with electron-donating, electron-withdrawing groups on the phenyl...