Investigating the role of kindlin-3 in protein translation and tumorigenesis via interaction with RACK1

Kindlins are a family of three FERM-containing cytoplasmic proteins that are expressed in various cell types. Kindlins modulate cell-cell and cell-Extracellular Matrix (ECM) interaction by regulating the ligand-binding affinity and avidity of the cell surface adhesion molecules-integrins. Kindlin-3...

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Bibliographic Details
Main Author: Qu, Jing
Other Authors: Tan Suet Mien
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/73451
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Institution: Nanyang Technological University
Language: English