Lipid perturbation compromises UPR-mediated ER homeostasis

Phospholipid homeostasis in biological membranes is essential to maintain cellular functions of organelles such as the endoplasmic reticulum (ER). Obesity has been associated to the perturbation of the ratio of the two most abundant phospholipids in the ER, phosphatidylcholine (PC) and phosphatidyle...

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Bibliographic Details
Main Author: Ng, Benjamin Si Han
Other Authors: Guillaume Thibault
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74173
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Institution: Nanyang Technological University
Language: English
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