Towards X-ray crystallographic characterization of nucleosome interactions with linker histones, FOXA proteins and high mobility group N factors

In the eukaryotic cell nucleus, genetic material is packaged into chromatin, consisting of arrays of nucleosomes that can be densely compacted. The three-dimensional organization of chromatin imparts a sophisticated temporally and spatially controlled regulation of accessibility to the genes. Global...

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Bibliographic Details
Main Author: Ravi, Sailatha
Other Authors: Curtis Alexander Davey
Format: Theses and Dissertations
Language:English
Published: 2018
Subjects:
Online Access:http://hdl.handle.net/10356/74380
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Institution: Nanyang Technological University
Language: English