An analysis of Talin methylation in leukocytes

• Main Author: Lim, Nicholas Kai Hung
• Other Authors: Su I-Hsin
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Science::Biological sciences::Microbiology::Immunology
• Online Access: http://hdl.handle.net/10356/74990
• Institution: Nanyang Technological University

As an integrin activator, Talin links the actin cytoskeleton of the migrating cell to membrane-bound integrin molecules, forming integrin-rich structures known as focal adhesions. Cell displacement is achieved by the resistance of actin retrograde flow by integrin-bound Talin1 in conjunction with...