Development of antifungal biopharmaceutical dectin1-FC fusion

• Main Author: Goh, Melody
• Other Authors: Chen Wei Ning, William
• Format: Final Year Project
• Language: English
• Published: 2018
• Subjects: DRNTU::Engineering::Bioengineering
• Online Access: http://hdl.handle.net/10356/75181
• Institution: Nanyang Technological University

Invasive fungal infections are a neglected category of disease that has a high mortality and implicated in immunocompromised patients. Dectin-1 (CLEC7A) is a type II transmembrane C-type lectin pattern recognition receptor expressed on innate immune cells such as macrophages, monocytes and neutrophi...